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Regulated
expression of microinjected DNA in adult Aedes aegypti mosquitoes. Isoe
J,Kunz S, Manhart C, Wells MA, Miesfeld RL. Insect Mol Biol.16(1):83-92
(2007).
Analysis of whole body ammonia
metabolism in Aedes aegypti using [15N]-labeled compounds and mass
spectrometry. Patricia Y. Scaraffia, Qingfen Zhang, Vicki H. Wysocki,
Jun Isoe and Michael A. Wells Insect Biochem Mol Biol, 36: 614-622.
(2006).
Reevaluation of the Role of
Early Trypsin Activity in the Transcriptional Activation of the Late
Trypsin Gene in the Mosquito Aedes aegypti. S.J. Lu, J.E. Pennington,
A.R. Stonehouse, M.M. Mobula, and M.A. Wells. Insect Biochem. Molec.
Biol. 36, 336-343 (2006).
Fragmentation Pathway for
Glutamine Identification: Loss of 73 Da from Dimethylformamidene
Isobutyl Glutamine. Q. Zhang, P.Y. Scaraffia, M. A. Wells, V.H.
Wysocki. J. Am. Soc. Mass Spectrom. 16:1192-203. (2005).
Evolution of insect
metamorphosis: A microarray-based study of larval and adult gene
expression in the ant Camponotus festinatus.Goodisman, M. A. D., J.
Isoe, D. E. Wheeler, and M. A. Wells. Evolution: Int J Org Evolution.
59:858-70
(2005).
Ammonia Metabolism in Aedes
aegypti. P.Y. Scaraffia, J. Isoe, A. Murillo and M.A. Wells, Insect
Biochem. Molec. Biol. 35: 491-503 (2005)
Sphingomyelinase D from venoms
of brown spiders: evolutionary insights from cDNA sequences and gene
structure. G.J. Binford, M.H.J. Cordes and M.A Wells. Toxicon 45:547-60
(2005).
cAMP-Dependent Protein Kinase of
Manduca sexta Phosphorylates but does not Activate the Fat Body
Triglyceride Lipase. R. Patel, J. L Soulages, M.A. Wells and E. L.
Arrese. Insect Biochem. Molec. Biol. 34:1269-1279 (2004).
The Basis
for Colorless Hemolymph and Cocoons in the Y-gene recessive B. mori
Mutants: A Defect in the Cellular Uptake of Carotenoids. K. Tsuchida,
C. Katagiri, Y.Tanaka, H. Tabunoki, R. Sato, H. Maekawa, N. Takada, Y.
Banno, H. Fujii, M. A. Wells, and Z. E. Jouni, J. Insect Physiol.
50:975-983
(2004).
Utilization
of Pre-existing Energy Stores during Blood Meal Digestion in Female
Aedes aegypti Mosquitoes. G. Zhou, J. E. Pennington and M. A. Wells,
Insect Biochem. Molec. Biol. 34: 919-925 (2004).
The effect
of larval and adult nutrition on successful autogenous egg production
by a mosquito. Telang A. and Wells M.A. J. Insect Physiol. 50:677-85
(2004).
Characterization
of the carotenoid-binding protein of the Y-gene dominant mutants of
Bombyx mori. K. Tsuchida, Z.E. Jouni, J. Gardetto, Y. Kobayashi, H.
Tabunoki, M. Azuma, H. Sugiyama, N. Takada, H. Maekawa, Y. Banno, H.
Fujii, H. Iwano and M. A. Wells, Insect Physiol 50, 363-7 (2004).
Lipid
Transfer Particle Mediates the Delivery of Diacylglycerol from
Lipophorin to Fat Body in Larval Manduca sexta. L. E. Canavoso, H. K.
Yun, Z. E. Jouni and M. A. Wells J. Lipid Res. 45, 456-465 (2004).
Metabolic
fate of [14C]-labeled meal protein amino acids in Aedes aegypti
mosquitoes, G. Zhou, M. Flowers, K. Friedrich, J. Horton, J. E.
Pennington and M. A. Wells, J. Insect Physiol 50, 337-349 (2004).
Proline can
be Utilized as an Energy Substrate during Flight of Aedes aegypti
Females. P.Y. Scaraffia and M.A. Wells, J. Insect Physiol. 49, 591-601
(2003).
The
phylogenetic distribution of sphingomyelinase D activity in venoms of
Haplogyne spiders. G.J. Binford and M.A Wells. Comparative Biochemistry
and Physiology Part B: Biochemistry and Molecular Biology 135, 25-33
(2003).
The Role of
Hemolymph Proline as a Transient Nitrogen Sink during Blood Meal
Digestion by the Mosquito, Aedes aegypti. D.A. Goldstrom J.E.
Pennington and M.A. Wells, J. Insect Physiol. 49, 115-121 (2003).
Transfer of
Cholesterol and Diacylglycerol from Lipophorin to Bombyx mori Ovarioles
in vitro: Role of the Lipid Transfer Particle. Z.E. Jouni, N. Takada,
J. Gazard, H. Maekawa, M.A. Wells, and K. Tsuchida. Insect Biochem.
Molec. Biol. 33, 145-153 (2003).
Comparative
Genome and Proteome Analysis of Anopheles gambiae and Drosophila
melanogaster. Zdobnov EM, Von Mering C, Letunic I, Torrents D, Suyama
M, Copley RR, Christophides GK, Thomasova D, Holt RA, Subramanian GM,
Mueller HM, Dimopoulos G, Law JH, Wells MA, Birney E, Charlab R,
Halpern AL, Kokoza E, Kraft CL, Lai Z, Lewis S, Louis C, Barillas-Mury
C, Nusskern D, Rubin GM, Salzberg SL, Sutton GG, Topalis P, Wides R,
Wincker P, Yandell M, Collins FH, Ribeiro J, Gelbart WM, Kafatos FC,
Bork P. Science 298, 149-159 (2002).
Characterization
of Cholesterol Transport from Midgut to Fat Body in Manduca sexta
Larvae H. K. Yun, Z. E. Jouni and M. A. Wells, Insect Biochem. Molec.
Biol. 32, 1151-1158 (2002).
Triacylglycerol-Rich
Lipophorins are found only in the Dipteran Infraorder Culicomorrpha. J.
E. Pennington and M. A. Wells. J. Insect Sci. 2.15. Available online:
insectscience.org/2.15.
Cholesterol
Efflux from Larval Manduca sexta Fat Body: High Density Lipophorin as
the Acceptor. Z. E. Jouni, H. K. Yun and M. A. Wells, J. Insect Physiol
48 609-618 (2002).
b -Cyclodextrin Facilitates
Cholesterol Efflux from Larval Manduca sexta Fat Body and Midgut in
vitro. Z. E. Jouni, B. McGill and M. A. Wells. Comp. Biochem. Physiol.
B 132, 699-709 (2002).
Absorption
and Tissue Distribution of Cholesterol in Manduca sexta. Z. E. Jouni,
J. Zamora and M. A. Wells, Arch. Insect Biochem. Physiol. 49, 167-175
(2002).
Midgut
Exopeptidase Activities in Aedes aegypti are Induced by Blood Feeding.
F.G. Noriega, K.A. Edgar, R. Bechet, M.A. Wells J. Insect Physiol. 48,
205-212 (2002).
Fat
Metabolism in Insects. L. E. Canavoso, Z. E. Jouni, K. J. Karnas, J. E.
Pennington and M. A. Wells, Annu. Rev. Nutr. 21, 23-46 (2001).
Role of
Lipid Transfer Particle in Delivery of Diacylglycerol from Midgut to
Lipophorin in Larval Manduca Sexta. L. E. Canavoso and M. A. Wells,
Insect Biochem. Molec. Biol. 31, 783-90 (2001).
Neuroendocrine
Factors Affecting the Steady State Levels of Early Trypsin mRNA in
Aedes aegypti. F. G. Noriega, K. A. Edgar, W. G. Goodman, D. K. Shah,
and M. A. Wells, J. Insect Physiol. J. Insect Physiol. 47, 515-522
(2001).
Diacylglycerol
Transport in the Insect Fat Body: Evidence of Involvement of Lipid
Droplets and the Cytosolic Fraction. E. L. Arrese, J. L. Gazard, M. T.
Flowers and M. A. Wells, J. Lipid Res. 42, 225-234 (2001).
Fat Body
Fructose-2,6-Bisphosphate Content and Phosphorylase Activity Correlate
with Changes in Hemolymph Glucose Concentration during Fasting and
Re-feeding in Larval Manduca sexta. J. R. Meyer-Fernandes, C. P. Clark,
K. C. Gondim and M. A. Wells, Insect Biochem. Molec. Biol. 31 165-170
(2001).
Lipid
Storage and Mobilization in Insects: Current Status and Future
Directions. E. L. Aresse, L. E. Canavoso, Z. E. Jouni, J. E.
Pennington, K. Tsuchida, and M. A. Wells, Insect Biochem. Molec. Biol.
31, 7-17 (2001).
Metabolic
Pathways for Diacylglycerol Biosynthesis and Release in the Midgut of
Larval Manduca sexta. L. E. Canavoso and M. A. Wells, Insect Biochem.
Molec. Biol. 30, 1173-1180 (2000).
Ectonucleotide
Diphospohydrolase Activities in Hemocytes of Larval Manduca sexta. J.
R. Meyer-Fernandes, H. Lanz-Mendoza, K. C. Gondim, E. Willott, and M.
A. Wells. Arch. Biochem. Biophys. 382 152-159, 2000.
a-Cyclodextrin
Extracts Diacylglycerol from Insect High-Density Lipoproteins. Z. E.
Jouni, J. Zamora, M. Snyder, William R. Montfort, Andrzej Weichsel and
M. A. Wells, J. Lipid. Res. 41, 933-939 (2000).
Allosteric
Effectors and Trehalose Protect Larval Manduca sexta Fat Body Glycogen
Phosphorylase B against Thermal Denaturation. J. R. Meyer-Fernandes, E.
L. Arrese, and M. A. Wells, Insect Biochem. Molec. Biol. 30, 473-478
(2000).
Developmental
Changes in the Response of Larval Manduca sexta Fat Body Glycogen
Phosphorylase to Starvation, Stress and Octopamine. J. R.
Meyer-Fernandes, K. C. Gondim and M. A. Wells, Insect Biochem. Molec.
Biol. 30, 415-422 (2000).
Characterization
of Lipophorin Binding to the Midgut of Larval Manduca sexta. K. C.
Gondim and M. A. Wells, Insect Biochem. Molec. Biol. 30, 405-423 (2000).
Recombinant
Juvenile Hormone Esterase, an Effective Tool to Modify Juvenile
Hormone-Dependent Gene Expression in Mosquitoes. K. A. Edgar, F. G.
Noriega, B. C. Bonning and M. A. Wells, Insect Molec. Biol. 9, 27-31
(2000).
cDNA and
Deduced Amino Acid Sequence of Apolipophorin-IIIs from Bombyx mori and
Bombyx mandarina. Y. Yamauchi, C. Hoeffer, A. Yamamoto, H. Takeda, R.
Ishihara, H. Maekawa, R. Sato, S. Su-Il, M. Sumida, M. A. Wells and K.
Tsuchida, Arch. Insect Biochem. Physiol. 43, 16-21 (2000).
A Molecular
View of Trypsin Synthesis in the Midgut of Aedes aegypti, F. G. Noriega
and M. A. Wells, J. Insect Physiol. 45, 613-620 (1999).
Increase in
the Size of the Amino Acid Pool is Sufficient to Activate Translation
of Early Trypsin mRNA in Aedes aegypti Midgut. F. G. Noriega, A. E.
Colonna and M. A. Wells Insect Biochem. Molec. Biol. 29, 243-247 (1999).
Calcium and
cAMP are Second Messengers in the Adipokinetic Hormone-Induced
Lipolysis of Triacylglycerols in the Manduca sexta Fat Body. E. L.
Arrese, M. T. Flowers, J. L. Gazard and M. A. Wells, J. Lipid Res. 40,
556-564 (1999).
Role of
Glycosylation in the Lipid-Binding Activity of the
Exchangeable-Apolipoprotein, Apolipophorin-III. J. L. Soulages, J.
Pennington, O. Bendavid, and M. A. Wells, Biochem. Biophys. Res.
Commun. 243, 372-376 (1998).
cDNA Cloning
and Pattern of Expression of an Adult, Female-Specific Chymotrypsin
from Aedes aegypti Midgut. Q. Jiang, M. Hall and M. A. Wells Insect
Biochem. Molec. Biol.27, 283-289 (1997).
Purification
and Properties of a Lipid Transfer Particle from Bombyx mori.
Comparison to the Lipid Transfer Particle from Manduca sexta. K.
Tsuchida, J. L. Soulages, A. Moribayashi, K. Suzuki, H. Maekawa and M.
A. Wells, Biochim. Biophys. Acta 1337, 57-65 (1997).
Adipokinetic
Hormone-Induced Lipolysis in the Fat Body of an Insect, Manduca sexta:
Synthesis of sn-1,2-diacylglycerols. E. L. Arrese and M. A. Wells J.
Lipid Res. 38, 68-76 (1997).
Juvenile
Hormone Controls Early Trypsin Gene Transcription in the Midgut of
Aedes aegypti. F. G. Noriega, D. K. Shah and M. A. Wells, Insect Molec.
Biol. 6, 63-66 (1997).
The
Precursor Protein of the Structural Apolipoproteins of Lipophorin: cDNA
and Deduced Amino Acid Sequence. K. Sundermeyer, J. K. Hendricks, S. V.
Prasad, and M. A. Wells, Insect Biochem. Molec. Biol. 26, 735-738
(1996).
The Use of
Decapitated Insects to Study Lipid Mobilization in Adult Manduca Sexta:
Effects of Adipokinetic Hormone and Trehalose on Fat Body Lipase
Activity. E. L. Arrese, B. I. Rojas-Rivas and M. A. Wells, Insect
Biochem. Molec. Biol. 26, 775-782 (1996).
Purification
and Partial Characterization of a Lutein-Binding Protein from the
Midgut of the Silkworm, Bombyx mori. Z. E. Jouni and M. A. Wells, J.
Biol. Chem. 271, 14722-14726 (1996).
Mitochondrial
Cytochrome C Oxidase Subunit I of Manduca sexta and a Comparison with
Other Invertebrate Genes. D. R. Frohlich, B. A. Steveneson, A. M.
Peterson and M. A. Wells, Comp. Biochem. Physiol 113B, 785-788 (1996).
Role of
Diacylglycerol and Apolipophorin-III in Regulating the Physiochemical
Properties of the Lipophorin Surface: Metabolic Implications. J. L.
Soulages, R. van Antwerpen, and M. A. Wells, Biochemistry 35, 5191-5198
(1996).
Early
Trypsin, a Female-specific Midgut Protease in Aedes Aegypti: Isolation,
Amino-terminal Sequence Determination, and Cloning and Sequencing of
the Gene. F. G. Noriega, X.-Y. Wang, J. E. Pennington, C. V.
Barillas-Mury and M. A. Wells, Insect Biochem. Molec. Biol. 26, 119-126
(1996).
Low
Concentrations of Diacylglycerol Promote the Binding of
Apolipophorin-III to a Phospholipid Surface: A Surface Plasmon
Resonance Spectroscopy Study. J. L. Soulages, Z. Salamon, M. A. Wells
and G. Tollin, Proc. Natl. Acad. Sci. U.S.A. 92, 5650-5654 (1995).
Purification,
Characterization and cDNA Sequence of an Alkaline Chymotrypsin from the
Midgut of Manduca sexta. A. M. Peterson, G. J. P. Fernando and M. A.
Wells, Insect Biochem. Molec. Biol. 25, 765-774 (1995).
Isolation
and Characterization of Apolipophorin-III from the Giant Water Bug
(Lethocerus medius). M. R. Kanost, K. A. Sparks and M. A.
Wells, Insect Biochem. Molec. Biol. 25, 759-764 (1995).
Early
Trypsin Activity is Part of the Signal Transduction System that
Activates Transcription of the Late Trypsin Gene in the Midgut of the
Mosquito, Aedes aegypti. C. V. Barillas-Mury, F. G. Noriega and M. A.
Wells, Insect Biochem. Molec. Biol. 25, 241-246 (1995).
Purification
and Properties of Glycogen-Phosphorylase from the Fat Body of Larval
Manduca sexta. E. L. Arrese, B. I. Rojas-Rivas and M. A. Wells, Insect
Biochem. Molec. Biol. 25, 209-216 (1995).
Exchangeable
Apolipoproteins of Insects Share a Common Structural Motif. A. F.
Smith, L. M. Owens, L. M. Strobel, H. Chen, M. R. Kanost, E. Hanneman
and M. A. Wells, J. Lipid Res. 35, 1976-1984 (1994).
Purification
and Properties of a Phosphorylatable Triacylglycerol Lipase from the
Fat Body of an Insect, Manduca sexta. E. L. Arrese and M. A. Wells, J.
Lipid Res. 35, 1652-1660 (1994).
Dietary
Control of Late-Trypsin Gene Transcription in Aedes aegypti. F. G.
Noriega, C. V. Barillas-Mury and M. A. Wells, Insect Biochem. Molec.
Biol. 24, 627-631 (1994).
Hydration
and Localization of Diacylglycerol in the Insect Lipoprotein,
Lipophorin. J. L. Soulages, M. Rivera, F. A. Walker and M. A. Wells,
Biochemistry 33, 3245-3251 (1994).
Sequence of
Three cDNAs Encoding an Alkaline Midgut Trypsin from Manduca sexta. A.
M. Peterson, C. V. Barillas-Mury and M. A. Wells. Insect Biochem.
Molec. Biology, 24, 463-471 (1994).
Effect of
Diacylglycerol Content on some Physiochemical Properties of the Insect
Lipoprotein, Lipophorin. Correlation with the Binding of
Apolipophorin-III. J. L. Soulages and M. A. Wells, Biochemistry 33,
2356-2362 (1994).
Cation-Promoted
Cyclic Voltammetry of Recombinant Rat Outer Mitochondrial Membrane
Cytochrome b5 at a Gold Electrode Modified with 8-Mercaptopropionic
Acid. M. Rivera, M. A. Wells and F. A. Walker, Biochemistry 33,
2161-2170 (1994).
Metabolic
Fate and Turnover Rate of Hemolymph Free Fatty Acids in Adult Manduca
sexta. J. L. Soulages and M. A. Wells, Insect Biochem. Molec. Biol. 24,
79-86 (1994).
Gene
Synthesis, Bacterial Expression and 1H NMR Spectroscopic Studies of the
Rat Outer Mitochondrial Membrane Cytochrome b5. M. Rivera, C.
Barillas-Mury, K. A. Christensen, J. W. Little, M. A. Wells and F. A.
Walker, Biochemistry 31, 12233-12240 (1992).
Oxygen-Carrying
Perfluorochemical Emulsions Improve Insect Fat Body Culture
Performance. F. G. Noriega and M. A. Wells, Insect Biochem. Molec.
Biol.
22, 585-590 (1992).
Biochemical
Insights Derived from Insect Diversity. J. H. Law, J. M. C. Ribeiro and
M. A. Wells, Annu. Rev. Biochemistry 61, 87-111 (1992).
Isolation
and Characterization of Two Follicle-Specific Proteins from Eggs of
Manduca sexta. K. Tsuchida, J. K. Kawooya, J. H. Law and M. A. Wells,
Insect Biochem. Molec. Biol. 22, 89-98 (1992).
Isolation,
Characterization, and cDNA Sequence of Two Fatty Acid-Binding Proteins
from the Midgut of Manduca sexta Larvae. A. F. Smith, K. Tsuchida, E.
Hanneman, T. C., Suzuki, and M. A. Wells, J. Biol. Chem. 267, 380-384
(1992).
cDNA and
Deduced Amino Acid Sequence of the Blood Meal-Induced Trypsin from the
Mosquito, Aedes aegypti. C. Barillas-Mury, R. Graf, H. H. Hagedorn, and
M. A. Wells, Insect Biochem. 21, 825-831 (1991).
Molecular
Structure of an Apolipoprotein Determined at 2.5 D Resolution. D. R.
Breiter, M. R. Kanost, M. M. Benning, J. H. Law, M. A. Wells, I.
Rayment and H. M. Holden, Biochemistry 30, 603-608 (1991).
Isolation and
Characterization of a Lipoprotein Receptor from the Fat Body of an
Insect, Manduca sexta. K. Tsuchida and M. A. Wells, J. Biol. Chem. 265,
5761-5767 (1990).
cDNA and Deduced Amino Acid Sequence
of the Blood Meal-Induced Trypsin from the Mosquito, Aedes aegypti. C.
Barillas-Mury, R. Graf, H. H. Hagedorn, and M. A. Wells, Insect
Biochem.
21, 825-831 (1991).
Insects as Biochemical Models.
J. H. Law and M. A. Wells, J. Biol. Chem. 264, 16335-16338 (1989).
Molecular Structure of an
Apolipoprotein Determined at 2.5 Å Resolution. D. R. Breiter,
M. R. Kanost, M. M. Benning, J. H. Law, M. A. Wells, I. Rayment and H.
M. Holden, Biochemistry 30, 603-608 (1991).
Adipokinetic Hormone Causes
Formation of a Low Density Lipophorin in the House Cricket, Acheta
domesticus. L. M. Strobel, M. R. Kanost, R. Ziegler and M. A. Wells,
Insect Biochem. 20, 859-863 (1990).
The Structure of the
Apolipophorin-III Gene from Manduca sexta. K. D. Cole, A. F. Smith and
M. A. Wells, Insect Biochem. 20, 381-388 (1990).
A Comparison of Adult and Larval
Manduca sexta Apolipophorin-III. K. D. Cole and M. A. Wells, Insect
Biochem. 20, 373-380 (1990).
Isolation and Characterization of
a Lipoprotein Receptor from the Fat Body of an Insect, Manduca sexta.
K. Tsuchida and M. A. Wells, J. Biol. Chem. 265, 5761-5767 (1990).
Effect of Diet on Triolein
Absorption in the Weanling Rat. C. A. Flores, P. M. Brannon, M. A.
Wells, M. Morrill and O. Koldovsky, Amer. J. Physiol. 258, G38-G44
(1990).
cDNA and Gene Sequence of Manduca sexta
Arylphorin, an Aromatic Amino Acid-Rich Larval Serum Protein:
Homology to Arthropod Hemocyanins. E. Willott, X-Y. Wang and M. A.
Wells, J. Biol. Chem. 264, 19052-19059 (1989).
Rates of Triolein Absorption in
Suckling and Adult Rats. C. A. Flores, S. A. O. Hing, M. A. Wells and
O. Koldovsky, Amer. J. Physiol. 257, G823-829 (1989).
A Strategy for Solubilizing
Delipidated Apolipoprotein with Lysophosphatidylcholine and
Reconstitution with Phosphatidylcholine. J. K. Kawooya, M. A. Wells and
J. H. Law, Biochemistry 28, 6658-6667 (1989).
Primary Structure of a Member of the
Serpin Superfamily of Proteinase Inhibitors from an Insect, Manduca
sexta. M. R. Kanost, S. V. Prasad and M. A. Wells, J. Biol. Chem. 264,
965-972 (1989).
Crystallization and Preliminary
Analysis of Crystals of Apolipophorin III Isolated from Locusta
migratoria. H. M. Holden, M. R. Kanost, J. H. Law, I. Rayment and M. A.
Wells, J. Biol. Chem. 263, 3960-3962 (1988).
Facilitated Diacylglycerol Exchange
between Insect Hemolymph Lipophorins. Properties of Manduca sexta Lipid
Transfer Particle. R. O. Ryan, K. R. Senthilathipan, M. A. Wells and J.
H. Law, J. Biol. Chem. 263, 14140-14145 (1988).
Sequential Structural Changes in the
Fat Body of the Tobacco Hornworm, Manduca sexta, during the Fifth
Larval Stadium. E. Willott, L. K. Bew, R. B. Nagle and M. A. Wells,
Tissue and Cell 20, 635-643 (1988).
Digestion, Absorption, Transport and
Storage of Fat during the Last Larval Instar of Manduca sexta. Changes
in the Role of Lipophorin in the Delivery of Dietary Lipid to the Fat
Body. K. Tsuchida and M. A. Wells, Insect Biochem. 18, 263-268 (1988).
Primary Structure of
Apolipophorin-III from the Migratory Locust, Locusta migratoria:
Potential Amphipathic Structures and Evolution of an Insect
Apolipoprotein. M. R. Kanost, M. S. Boguski, M. Freeman, J. I. Gordon,
G. R. Wyatt and M. A. Wells, J. Biol. Chem. 263, 10568-10573 (1988).
Effect of Dietary Lipid Content on
Lipid Transport and Storage during Larval Development of Manduca sexta.
G. J. P. Fernando-Warnakulasuriya, K. Tsuchida and M. A. Wells, Insect
Biochem. 18, 211-214 (1988).
Lipid Transport in Insects. J. P.
Shapiro, J. H. Law and M. A. Wells, Annu. Rev. Entomology 33, 297-318
(1988).
Changes in Lipophorin Composition
during the Fourth to Fifth Instar Molt of Manduca sexta. K. Tsuchida,
S. V. Prasad, and M. A. Wells, Insect Biochem. 17, 1139-1141 (1987).
Primary Structure and Comparative
Sequence Analysis of an Insect Apolipoprotein: Apolipophorin-III from
Manduca sexta. K. D. Cole, G. J. P. Fernando-Warnakulasuriya, M. S.
Boguski, M. Freeman, J. I. Gordon, W. A. Clark, J. H. Law and M. A.
Wells, J. Biol. Chem. 262, 11794-11800 (1987).
Intact Biliary Excretion of
Gastrically Administered Prostaglandin F2 in Rats: Developmental
Differences. A. D. Bedrick, M. A. Wells, D. L. Ford and O. Koldovsky,
Am. J. Physiol. 253, G787-G792 (1987).
The Role of Apolipophorin-III in in
vivo Lipoprotein Interconversions in Adult Manduca sexta. M. A. Wells,
R. O. Ryan, J. K. Kawooya, and J. H. Law, J. Biol. Chem. 262, 4172-4176
(1987).
Lipoprotein Biosynthesis in the
Larvae of the Tobacco Hornworm, Manduca sexta. S. V. Prasad, G. J. P.
Fernando-Warnakulasuriya, M. Sumida, J. H. Law, and M. A. Wells. J.
Biol. Chem. 261, 17174-17176 (1986).
Physical and Surface Properties of
Insect Apolipophorin III. J. K. Kawooya, S. C. Meredith, M. A. Wells,
F. J. Kezdy, and J. H. Law. J. Biol. Chem. 261, 13588-13591 (1986).
Halothane-Induced Changes in
Acetylcholine Receptor Channel Kinetics are Attenuated by Cholesterol.
J. Lechleiter, M. Wells and R. Gruener, Biochim. Biophys. Acta 856,
640-645 (1986).
Lipid Transfer Protein from Manduca
sexta. R. O. Ryan, M. A. Wells, and J. H. Law. Biochem. Biophys. Res.
Commun. 136, 260-265 (1986).
Lipoprotein Interconversions in an
Insect, Manduca sexta. R. O. Ryan, S. V. Prasad, E. J. Henriksen, M. A.
Wells and J. H. Law, J. Biol. Chem. 261, 563-568 (1986).
Changes in Lipoprotein Composition
during Larval-Pupal Metamorphosis of an Insect, Manduca sexta. S. V.
Prasad, R. O. Ryan, J. H. Law and M. A. Wells, J. Biol. Chem. 261,
558-562 (1986).
Dihexanolyphosphatidylethanolamine:
Effect of Head Group Charge on Rates of Alkaline and Phospholipase A2
Catalyzed Hydrolyses. P. Kanda and M. A. Wells, Chem. Phys. Lipids 39,
31-39 (1986).
A Novel Procedure for the
Purification of Apolipophorin III. M. A. Wells, R. O. Ryan, S. V.
Prasad, and J. H. Law, Insect Biochem. 15, 565-571 (1985).
Purification and Properties of a
Predominantly Female-Specific Protein from the Hemolymph of the Larva
of the Tobacco Hornworm, Manduca sexta. R. O. Ryan, P. S. Keim, M. A.
Wells and J. H. Law, J. Biol. Chem. 260, 782-787 (1985).
D-Dihexanoylphosphatidylcholine is
Not a Pure Competitive Inhibitor of Phospholipase A2 Hydrolysis of
L-Dihexanoylphosphatidylcholine. P. Kanda and M. A. Wells, Chem. Phys.
Lipids 37, 251-256 (1985).
Lipoprotein Metabolism in Suckling
Rats: Characterization of Plasma and Lymphatic Lipoproteins. G. J. P.
Fernando-Warnakulasuriya, M. L. Eckerson, W. A. Clark and M. A. Wells,
J. Lipid Res. 24, 1626-1638 (1983).
Metabolism of Branched-chain Keto
Acids in Neonatal Rat Liver Perfusions. S. C. Frost and M. A. Wells,
Arch. Biochem. Biophys. 226, 425-432 (1983).
Studies on Fat Digestion,
Absorption, and Transport in the Suckling Rat. IV. In vivo Rates of
Triacylglycerol Secretion by Intestine and Liver. S. C. Frost, W. A.
Clark, and M. A. Wells, J. Lipid Res. 24, 899-903 (1983).
Studies on Fat Digestion,
Absorption, and Transport in the Suckling Rat. III. Composition of Bile
and Evidence for Enterohepatic Circulation of Bile Salts. J. E.
Staggers, S. C. Frost, and M. A. Wells, J. Lipid Res. 23, 1143-1151
(1982).
Effect of the Oral Hypoglycemic
Agent 2-Tetradecylglycidic Acid on Fatty Acid Oxidation in Suckling
Rats In vivo and in Perfused Liver. S. C. Frost and M. A. Wells, Arch.
Biochem. Biophys. 211, 547-555 (1981).
A Comparison of the Utilization of
Medium and Long Chain Fatty Acids for Oxidation and Ketogenesis in the
Suckling Rat: In vivo and In vitro Studies. S. C. Frost and M. A.
Wells,
Arch. Biochem. Biophys. 211, 537-546 (1981).
Thermodynamics of
Dihexanoylphosphatidylcholine Aggregation. R. E. Johnson, M. A. Wells
and J. A. Rupley, Biochemistry 20, 4239-4242 (1981).
Synthesis of
1-sn-Glycerophosphorylcholine.
P. Kanda and M. A. Wells, J. Lipid Res. 22, 879-882 (1981).
Facile Acylation of
Glycerophosphorylcholine Catalyzed by Trifluoroacetic Anhydride. P.
Kanda and M. A. Wells, J. Lipid Res. 22, 877-879 (1981).
Studies on Fat Digestion, Absorption
and Transport in the Suckling Rat. II. Triacylglycerols:
Molecular Species, Stereospecific Analysis and Specificity of
Hydrolysis by Lingual Lipase. J. E. Staggers, G. J. P.
Fernando-Warnakulasuriya and M. A. Wells, J. Lipid Res. 22, 675-679
(1981).
Studies on Fat Digestion, Absorption
and Transport in the Suckling Rat. I. Fatty Acid Composition and
Concentration of Major Lipid Components. G. J. P.
Fernando-Warnakulasuriya, J. E. Staggers, S. C. Frost and M. A. Wells,
J. Lipid Res. 22, 668-674 (1981).
A Further Examination of the Active
Form of Crotalus adamanteus Phospholipase A2. C. M. Smith and M. A.
Wells, Biochim. Biophys. Acta 663, 687-694 (1981).
A Simplified Procedure for the
Preparation of 2,3-0-Isoproplyidene-sn-Glycerol from L-Arabinose. P.
Kanda and M. A. Wells, J. Lipid Res. 21, 257-258 (1980).
Phospholipase D from Savoy Cabbage:
Purification and Preliminary Kinetic Characterization. T. T. Allgyer
and M. A. Wells, Biochemistry 18, 5348-5353 (1979).
Thermodynamic Models for Micelle
Formation by Phosphatidylcholines Containing Short Chain Fatty Acids:
Correlations with Physical Chemical Data and the Effects of
Concentration on the Activity of Phospholipase A2. T. T. Allgyer and M.
A. Wells, Biochemistry 18, 4354-4361 (1979).
Intramolecular Catalysis of Ester
Hydrolysis by Metal Complexed Hydroxide Ion. Acyl Oxygen Bond Sission
in Co+2 Carboxylic Acid Complexes. M. A. Wells and T. C. Bruice, J. Am.
Chem. Soc. 99, 5341-5356 (1977).
Ultracentrifugation of Hydrated Egg
Lecithin in Benzene Solution. P H. Poon and M. A. Wells, Chem. Phys.
Lipids 18, 205-211 (1977).
1-Hydroxy-2-tert-Butyl-Dimethylsilyl-sn-Glycero-3-Phosphorylcholine.
A Useful Intermediate in the Synthesis of Short Acyl Chain
1-Acyl-sn-Glycero-3-Phosphorylcholines.
K. K. Yabusaki and M. A. Wells, Chem. Phys. Lipids 17, 120-127 (1976).
Intramolecular Hydrolysis of Methyl
Ester by Substrate Bound Metal Hydroxide. M. A. Wells, G. A. Rogers and
T. C. Bruice, J. Am. Chem. Soc. 98, 4336-4338 (1976).
Phospholipase A2 as a Probe of
Phospholipid Distribution in Erythrocyte Membranes. Factors Influencing
the Apparent Specificity of the Reaction. J. K. Martin, M. G. Luthra,
M. A. Wells, R. P. Watts, and D. J. Hanahan. Biochemistry 14, 5400-5408
(1975).
Essential Fatty Acid Deficiency in
Human Adults during Parenteral Nutrition. M. C. Riella, J. W. Broviac,
M. A. Wells, B. H. Scribner, Ann. Int. Med. 83, 786-789 (1975).
A Simple and High Yield Purification
of Crotalus adamanteus Phospholipase A2. M. A. Wells, Biochim. Biophys.
Acta 380, 501-505 (1975).
Binding of Calcium to
Phosphatidylcholine as Determined by Proton Magnetic Resonance and
Infrared Spectroscopy. K. K. Yabusaki and M. A. Wells, Biochemistry 14,
162-166 (1975).
The Nature of Water Inside
Phosphatidylcholine Micelles in Diethyl Ether. M. A. Wells,
Biochemistry
13, 4937-4941 (1974).
Physical Studies of Egg
Phosphatidylcholine Micelles in Diethyl Ether-Water Solutions. P. H.
Poon and M. A. Wells, Biochemistry 13, 4928-4936 (1974).
The Activity of Phospholipase A2 in
Reversed Micelles of Phosphatidylcholine in Diethyl Ether: Effect of
Water and Cations. R. L. Misiorowski and M. A. Wells, Biochemistry 13,
4921-4927 (1974).
The Effect of pH on the Kinetic and
Spectral Properties of Crotalus adamanteus Phospholipase A2 in H2O and
D2O.
M. A. Wells, Biochemistry 13, 2265-2268 (1974).
A Phospholipase A2 Model System.
Calcium Enhancement of the Amine-Catalyzed Methanolysis of
Phosphatidylcholine. M. A. Wells, Biochemistry 13, 2258-2264 (1974).
The Mechanism of Interfacial
Activation of Phospholipase A2. M. A. Wells, Biochemistry 13, 2248-2257
(1974).
A Facile Synthesis of 1-Acyl
Ethylene Glycol-2- Phosphorylcholines. K. K. Yabusaki and M. A. Wells,
Biochim. Biophys. Acta. 296, 546-548 (1973).
Effects of Chemical Modification on
the Activity of Crotalus adamanteus Phospholipase A2. Evidence for an
Essential Amino Group. M. A. Wells, Biochemistry 12, 1086-1093 (1973).
Spectral Perturbations of Crotalus
adamanteus Phospholipase A2 Induced by Divalent Cation Binding. M. A.
Wells, Biochemistry 12, 1080-1085 (1973).
Competition between Cations and
Water for Binding to Phosphatidylcholines in Organic Solvents. R. L.
Misiorowski and M. A. Wells, Biochemistry 12, 967-975 (1973).
A Kinetic Study of the Phospholipase
A2 (Crotalus adamanteus) Catalyzed Hydrolysis of
1,2-Dibutyryl-sn-glycero-3-phosphorylcholine.
M. A. Wells, Biochemistry 11, 1030-1041 (1972).
Observations on the Phospholipase A2
of Crotalus atrox. Molecular Weight and Other Properties. Y. Hachimori,
M. A. Wells, and D. J. Hanahan, Biochemistry 10, 4084-4089 (1971).
Spectral Peculiarities of the
Monomer-Dimer Transition of the Phospholipase A2 of Crotalus adamanteus
Venom. M. A. Wells, Biochemistry 10, 4078-4083 (1971).
Evidence that the Phospholipases A2
of Crotalus adamanteus Venom are Dimers. M. A. Wells, Biochemistry 10,
4074-4078 (1971).
Evidence for O-Acyl Cleavage during
Hydrolysis of 1,2-Diacyl-sn-Glycero-3-Phosphorylcholine by the
Phospholipase A2 of Crotalus adamanteus Venom. M. A. Wells, Biochim.
Biophys. Acta 248, 80-86 (1971).
The Cholesterol Solubilizing
Capacity of Lecithin in Aqueous Solutions of Bile Salts. D. R. Saunders
and M. A. Wells, Biochim. Biophys. Acta 176, 828-835 (1969).
Studies on Phospholipase A. I.
Isolation and Characterization of Two Enzymes from Crotalus adamanteus
Venom. M. A. Wells and D. J. Hanahan, Biochemistry 8, 414-424 (1969).
Phospholipase A2 from C. adamanteus
Venom. M. A. Wells and D. J. Hanahan, Methods in Enzymology 14, 178-184
(1969).
Quantitative and Qualitative Analysis
of Lipids and Lipid Components. J. C. Dittmer and M. A. Wells, Methods
in Enzymology 14, 482-530 (1969).
A Comprehensive Study of the
Postnatal Changes in the Concentration of the Lipids of Developing Rat
Brain. M. A. Wells and J. C. Dittmer, Biochemistry 6, 3169-3175 (1967).
A Microanalytical Technique for the
Quantitative Determination of Twenty-four Classes of Brain Lipids. M.
A. Wells and J. C. Dittmer, Biochemistry 5, 3405-3418 (1966).
The Identification of
Glycerophosphorylglycerol Phosphate as the Deacylation Product of a New
Brain Lipid. M. A. Wells and J. C. Dittmer, J. Biol. Chem. 241,
2103-2105 (1966).
The Quantitative Extraction and
Analysis of Brain Polyphosphoinositides. M. A. Wells and J. C. Dittmer,
Biochemistry 4, 2459-2468 (1965).
A Preparative Method for the
Isolation of Brain Cerebroside, Sulfatide and Sphingomyelin. M. A.
Wells and J. C. Dittmer, J. Chrom. 18, 503-511 (1965).
The Use of Sephadex for the Removal
of Nonlipid Contaminants from Lipid Extracts. M. A. Wells and J. C.
Dittmer, Biochemistry 2, 1259-1263 (1963).
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