Educational Publications

1.          Improving Undergraduate Biology Education in a Large Research University. C. Bender, S. Ward and M. A. Wells, Molec. Biol. Cell, 5, 129-134 (1994).

2.          An Electronic Companion to Biochemistry, M. A. Wells and J. L. Tupy, Cogito Learning Media, Inc., New York and San Francisco (1998). A CD ROM-based multimedia review of biochemistry.

3.          Pulse of the Planet radio program on silkworms. Three programs broadcast in August 2001 -http://pulseplanet.nationalgeographic.com.

Chapters and Reviews

1.          Quantitative and Qualitative Analysis of Lipids and Lipid Components. J. C. Dittmer and M. A. Wells, Methods in Enzymology 14, 482-530 (1969).

2.          Phospholipase A₂ from C. adamanteus Venom. M. A. Wells and D. J. Hanahan, Methods in Enzymology 14, 178-184 (1969).

3.          The Nucleophilicity of Metal Bound Hydroxide, Mechanisms of Displacement on Esters, and Transesterification Involving the Metal Acyl Anhydride Bond. M. A. Wells and T. C. Bruice. In: (B. Pullman and N. Goldblum, eds.), "Metal Ligand Interactions in Organic and Biochemistry", (1976), D. Reidel Pub. Co., Part 2, p. 273-284.

4.          Natural Abundance Carbon-13 Magnetic Resonance Study of Phospholipase A₂ from Crotalus adamanteus. D. J. Nelson, W. C. Hutton, and M. A. Wells. In: (R. H. Wasserman et al., Eds.) "Calcium Binding Proteins and Calcium Function" (1977) Elseveir North-Holland, Inc., pp. 82-84.

5.          Interfacial Activation of Phospholipase A₂. M. A. Wells. In: (C. Galli et al., eds) "Advance in Prostaglandin and Thromboxane Research" (1978), Raven Press, Vol. 3, pp. 39-45.

6.          Kinetic Anomalies Associated with Phospholipase A₂ Hydrolysis of Micellar Substrates. T. T. Allgyer and M. A. Wells. In: (S. Gatt, L. Freysz, P. Mandel, Eds.) "Enzymes of Lipid Metabolism" (1978) Plenum Publishing Corp., pp. 153-163.

7.          Natural Abundance Carbon-13 NMR Studies of Conformational Transitions in Calcium-Binding Proteins. D. J. Nelson, S. J. Opella, W. C. Hutton, and M. A. Wells. In: (P. F. Agris, ed.), "Biomolecular Structure and Function", (1978), Academic Press, pp. 393-394.

8.          Glyceride Digestion. M. A. Wells and N. A. DiRenzo. In: (P. Boyer, Ed.) "The Enzymes” 3rd edition, vol. 16, p. 113-139 (1983).

9.          The Dynamics of Lipophorin Interconversions in Manduca sexta. R. O. Ryan, M. A. Wells, and J. H. Law. In: (J. H. Law, Ed.), "Molecular Entomology” UCLA Symposium on Molecular and Cellular Biology. New Series 49, pp. 257-266 (1987).

10.      Lipophorin Biosynthesis during the Life Cycle of the Tobacco Hornworm, Manduca sexta. S. V. Prasad, K. Tsuchida, K. D. Cole, and M. A. Wells. In: (J. H. Law, Ed.), "Molecular Entomology” UCLA Symposium on Molecular and Cellular Biology. New Series 49, pp. 267-273 (1987).

11.      Lipid Transport in Insects. J. P. Shapiro, J. H. Law and M. A. Wells, Annu. Rev. Entomology 33, 297-318 (1988).

12.      Insects as Biochemical Models. J. H. Law and M. A. Wells, J. Biol. Chem. 264, 16335-16338 (1989).

13.      Biochemical Insights Derived from Insect Diversity. J. H. Law, J. M. C. Ribeiro and M. A. Wells, Annu. Rev. Biochem. 61, 87-111 (1992).

14.      Purification of a Carotenoid-Binding Protein from the Midgut of the Silkworm, Bombyx mori. In: (L. M. Canfield, N. I. Krinsky, J. A. Olson, Eds.), “Carotenoids in Human Health” Ann. N. Y. Acad. Sci. 691, 210-212 (1993).

15.      Lipophorin: The Structure of an Insect Lipoprotein and Its Role in Lipid Transport in Insects. J. L. Soulages and M. A. Wells, Adv. Protein Chem. 45, 371-415 (1994).

16.      A Molecular View of Trypsin Synthesis in the Midgut of Aedes aegypti, F. G. Noriega and M. A. Wells, J. Insect Physiol. 45, 613-620 (1999).

17.      Lipid Storage and Mobilization in Insects: Current Status and Future Directions. E. L. Arrese, L. E. Canavoso, Z. E. Jouni, J. E. Pennington, K. Tsuchida, and M. A. Wells, Insect Biochem. Molec. Biol. 31, 7-17 (2001).

18.     Fat Metabolism in Insects. L. E. Canavoso, Z. E. Jouni, K. J. Karnas, J. E. Pennington and M. A. Wells, Annu. Rev. Nutr. 21, 23-46 (2001).

19.      Pennington, J. E. and Wells, M. A. The Midgut: Structure and Function in (Marquardt WC, Black WC, Freier J, Hagedorn H, Hemingway J, Higgs S, James AA and Kondratieff, Eds.) “Biology of Disease Vectors”, 2nd ed., Elsevier, 289-295 (2004).

20.      Zhou, G., Scaraffia, P. Y. Wells, M. A. Vector Nutrition and Energy Metabolism in (Marquardt WC, Black WC, Freier J, Hagedorn H, Hemingway J, Higgs S, James AA and Kondratieff, Eds.)  “Biology of Disease Vectors”, 2nd ed., Elsevier, 311-315 (2004).

21.      Isoe, J, Noriega, F. G. and Wells, M. A. Genomics and Gene Expression in Vectors in (Marquardt WC, Black WC, Freier J, Hagedorn H, Hemingway J, Higgs S, James AA and Kondratieff, Eds.) “Biology of Disease Vectors”, 2nd ed., Elsevier, 551-563, 2004.

Research Publications

1.          The Use of Sephadex for the Removal of Nonlipid Contaminants from Lipid Extracts. M. A. Wells and J. C. Dittmer, Biochemistry 2, 1259-1263 (1963).

2.          A Preparative Method for the Isolation of Brain Cerebroside, Sulfatide and Sphingomyelin. M. A. Wells and J. C. Dittmer, J. Chrom. 18, 503-511 (1965).

3.          The Quantitative Extraction and Analysis of Brain Polyphosphoinositides. M. A. Wells and J. C. Dittmer, Biochemistry 4, 2459-2468 (1965).

4.          The Identification of Glycerophosphorylglycerol Phosphate as the Deacylation Product of a New Brain Lipid. M. A. Wells and J. C. Dittmer, J. Biol. Chem. 241, 2103-2105 (1966).

5.          A Microanalytical Technique for the Quantitative Determination of Twenty-four Classes of Brain Lipids. M. A. Wells and J. C. Dittmer, Biochemistry 5, 3405-3418 (1966).

6.          A Comprehensive Study of the Postnatal Changes in the Concentration of the Lipids of Developing Rat Brain. M. A. Wells and J. C. Dittmer, Biochemistry 6, 3169-3175 (1967).

7.          Studies on Phospholipase A. I. Isolation and Characterization of Two Enzymes from Crotalus adamanteus Venom. M. A. Wells and D. J. Hanahan, Biochemistry 8, 414-424 (1969).

8.          The Cholesterol Solubilizing Capacity of Lecithin in Aqueous Solutions of Bile Salts. D. R. Saunders and M. A. Wells, Biochim. Biophys. Acta 176, 828-835 (1969).

9.          Evidence for O-Acyl Cleavage during Hydrolysis of 1,2-Diacyl-sn-Glycero-3-Phosphorylcholine by the Phospholipase A₂ of Crotalus adamanteus Venom. M. A. Wells, Biochim. Biophys. Acta 248, 80-86 (1971).

10.      Evidence that the Phospholipases A₂ of Crotalus adamanteus Venom are Dimers. M. A. Wells, Biochemistry 10, 4074-4078 (1971).

11.      Spectral Peculiarities of the Monomer-Dimer Transition of the Phospholipase A₂ of Crotalus adamanteus Venom. M. A. Wells, Biochemistry 10, 4078-4083 (1971).

12.      Observations on the Phospholipase A₂ of Crotalus atrox. Molecular Weight and Other Properties. Y. Hachimori, M. A. Wells, and D. J. Hanahan, Biochemistry 10, 4084-4089 (1971).

13.      A Kinetic Study of the Phospholipase A₂ (Crotalus adamanteus) Catalyzed Hydrolysis of 1,2-Dibutyryl-sn-glycero-3-phosphorylcholine. M. A. Wells, Biochemistry 11, 1030-1041 (1972).

14.      Competition between Cations and Water for Binding to Phosphatidylcholines in Organic Solvents. R. L. Misiorowski and M. A. Wells, Biochemistry 12, 967-975 (1973).

15.      Spectral Perturbations of Crotalus adamanteus Phospholipase A₂ Induced by Divalent Cation Binding. M. A. Wells, Biochemistry 12, 1080-1085 (1973).

16.      Effects of Chemical Modification on the Activity of Crotalus adamanteus Phospholipase A₂. Evidence for an Essential Amino Group. M. A. Wells, Biochemistry 12, 1086-1093 (1973).

17.      A Facile Synthesis of 1-Acyl Ethylene Glycol-2-Phosphorylcholines. K. K. Yabusaki and M. A. Wells, Biochim. Biophys. Acta. 296, 546-548 (1973).

18.      The Mechanism of Interfacial Activation of Phospholipase A₂. M. A. Wells, Biochemistry 13, 2248-2257 (1974).

19.      A Phospholipase A₂ Model System. Calcium Enhancement of the Amine-Catalyzed Methanolysis of Phosphatidylcholine. M. A. Wells, Biochemistry 13, 2258-2264 (1974).

20.      The Effect of pH on the Kinetic and Spectral Properties of Crotalus adamanteus Phospholipase A₂ in H₂O and D₂O. M. A. Wells, Biochemistry 13, 2265-2268 (1974).

21.      The Activity of Phospholipase A₂ in Reversed Micelles of Phosphatidylcholine in Diethyl Ether: Effect of Water and Cations. R. L. Misiorowski and M. A. Wells, Biochemistry 13, 4921-4927 (1974).

22.      Physical Studies of Egg Phosphatidylcholine Micelles in Diethyl Ether-Water Solutions. P. H. Poon and M. A. Wells, Biochemistry 13, 4928-4936 (1974).

23.      The Nature of Water Inside Phosphatidylcholine Micelles in Diethyl Ether. M. A. Wells, Biochemistry 13, 4937-4941 (1974).

24.      Binding of Calcium to Phosphatidylcholine as Determined by Proton Magnetic Resonance and Infrared Spectroscopy. K. K. Yabusaki and M. A. Wells, Biochemistry 14, 162-166 (1975).

25.      A Simple and High Yield Purification of Crotalus adamanteus Phospholipase A₂. M. A. Wells, Biochim. Biophys. Acta 380, 501-505 (1975).

26.      Essential Fatty Acid Deficiency in Human Adults during Parenteral Nutrition. M. C. Riella, J. W. Broviac, M. A. Wells, B. H. Scribner, Ann. Int. Med. 83, 786-789 (1975).

27.      Phospholipase A₂ as a Probe of Phospholipid Distribution in Erythrocyte Membranes. Factors Influencing the Apparent Specificity of the Reaction. J. K. Martin, M. G. Luthra, M. A. Wells, R. P. Watts, and D. J. Hanahan. Biochemistry 14, 5400-5408 (1975).

28.      Detection of Myelin in the Optic Nerve of Young Rats by Sedimentation Equilibrium in a CsCl Gradient. N. K. Detering and M. A. Wells, J. Neurochem. 26, 247-252 (1976).

29.      The Non-Synchronous Synthesis of Myelin Components during Early Stages of Myelination in the Rat Optic Nerve. N. K. Detering and M. A. Wells, J. Neurochem. 26, 253-257 (1976).

30.      Intramolecular Hydrolysis of Methyl Ester by Substrate Bound Metal Hydroxide. M. A. Wells, G. A. Rogers and T. C. Bruice, J. Am. Chem. Soc. 98, 4336-4338 (1976).

31.      1-Hydroxy-2-tert-Butyl-Dimethylsilyl-sn-Glycero-3-Phosphorylcholine. A Useful Intermediate in the Synthesis of Short Acyl Chain 1-Acyl-sn-Glycero-3-Phosphorylcholines. K. K. Yabusaki and M. A. Wells, Chem. Phys. Lipids 17, 120-127 (1976).

32.      Ultracentrifugation of Hydrated Egg Lecithin in Benzene Solution. P H. Poon and M. A. Wells, Chem. Phys. Lipids 18, 205-211 (1977).

33.      Intramolecular Catalysis of Ester Hydrolysis by Metal Complexed Hydroxide Ion. Acyl Oxygen Bond Sission in Co⁺² Carboxylic Acid Complexes. M. A. Wells and T. C. Bruice, J. Am. Chem. Soc. 99, 5341-5356 (1977).

34.      Fatty Acid and Molecular Species Composition of Rat Brain Phosphatidylcholine and -Ethanolamine from Birth to Weaning. C. G. Crawford and M. A. Wells, Lipids 14, 757-762 (1979).

35.      Thermodynamic Models for Micelle Formation by Phosphatidylcholines Containing Short Chain Fatty Acids: Correlations with Physical Chemical Data and the Effects of Concentration on the Activity of Phospholipase A₂. T. T. Allgyer and M. A. Wells, Biochemistry 18, 4354-4361 (1979).

36.      Phospholipase D from Savoy Cabbage: Purification and Preliminary Kinetic Characterization. T. T. Allgyer and M. A. Wells, Biochemistry 18, 5348-5353 (1979).

37.      Prevention of Essential Fatty Acid Deficiency during Prolonged Home Parenteral Nutrition. M. Riella, R. Miller, M. Wells and B. H. Scribner, Acta Chir. Scand., suppl. 494, 60 (1979).

38.      A Simplified Procedure for the Preparation of 2,3-0-Isoproplyidene-sn-Glycerol from L-Arabinose. P. Kanda and M. A. Wells, J. Lipid Res. 21, 257-258 (1980).

39.      A Further Examination of the Active Form of Crotalus adamanteus Phospholipase A₂. C. M. Smith and M. A. Wells, Biochim. Biophys. Acta 663, 687-694 (1981).

40.      Studies on Fat Digestion, Absorption and Transport in the Suckling Rat. I. Fatty Acid Composition and Concentration of Major Lipid Components. G. J. P. Fernando-Warnakulasuriya, J. E. Staggers, S. C. Frost and M. A. Wells, J. Lipid Res. 22, 668-674 (1981).

41.      Studies on Fat Digestion, Absorption and Transport in the Suckling Rat. II. Triacylglycerols:  Molecular Species, Stereospecific Analysis and Specificity of Hydrolysis by Lingual Lipase. J. E. Staggers, G. J. P. Fernando-Warnakulasuriya and M. A. Wells, J. Lipid Res. 22, 675-679 (1981).

42.      Facile Acylation of Glycerophosphorylcholine Catalyzed by Trifluoroacetic Anhydride. P. Kanda and M. A. Wells, J. Lipid Res. 22, 877-879 (1981).

43.      Synthesis of 1-sn-Glycerophosphorylcholine. P. Kanda and M. A. Wells, J. Lipid Res. 22, 879-882 (1981).

44.      Thermodynamics of Dihexanoylphosphatidylcholine Aggregation. R. E. Johnson, M. A. Wells and J. A. Rupley, Biochemistry 20, 4239-4242 (1981).

45.      A Comparison of the Utilization of Medium and Long Chain Fatty Acids for Oxidation and Ketogenesis in the Suckling Rat: In vivo and In vitro Studies. S. C. Frost and M. A. Wells, Arch. Biochem. Biophys. 211, 537-546 (1981).

46.      Effect of the Oral Hypoglycemic Agent 2-Tetradecylglycidic Acid on Fatty Acid Oxidation in Suckling Rats In vivo and in Perfused Liver. S. C. Frost and M. A. Wells, Arch. Biochem. Biophys. 211, 547-555 (1981).

47.      Effect of Inhibition of Fatty Acid Oxidation on Neonatal Liver Carnitine Content. S. C. Frost and M. A. Wells. Biochem. J. 204, 861-863 (1982).

48.      Studies on Fat Digestion, Absorption, and Transport in the Suckling Rat. III. Composition of Bile and Evidence for Enterohepatic Circulation of Bile Salts. J. E. Staggers, S. C. Frost, and M. A. Wells, J. Lipid Res. 23, 1143-1151 (1982).

49.      Studies on Fat Digestion, Absorption, and Transport in the Suckling Rat. IV. In vivo Rates of Triacylglycerol Secretion by Intestine and Liver. S. C. Frost, W. A. Clark, and M. A. Wells, J. Lipid Res. 24, 899-903 (1983).

50.      Metabolism of Branched-chain Keto Acids in Neonatal Rat Liver Perfusions. S. C. Frost and M. A. Wells, Arch. Biochem. Biophys. 226, 425-432 (1983).

51.      Lipoprotein Metabolism in Suckling Rats: Characterization of Plasma and Lymphatic Lipoproteins. G. J. P. Fernando-Warnakulasuriya, M. L. Eckerson, W. A. Clark and M. A. Wells, J. Lipid Res. 24, 1626-1638 (1983).

52.      D-Dihexanoylphosphatidylcholine is Not a Pure Competitive Inhibitor of Phospholipase A₂ Hydrolysis of L-Dihexanoylphosphatidylcholine. P. Kanda and M. A. Wells, Chem. Phys. Lipids 37, 251-256 (1985).

53.      Purification and Properties of a Predominantly Female-Specific Protein from the Hemolymph of the Larva of the Tobacco Hornworm, Manduca sexta. R. O. Ryan, P. S. Keim, M. A. Wells and J. H. Law, J. Biol. Chem. 260, 782-787 (1985).

54.      A Novel Procedure for the Purification of Apolipophorin III. M. A. Wells, R. O. Ryan, S. V. Prasad, and J. H. Law, Insect Biochem. 15, 565-571 (1985).

55.      Fatty Acid Metabolism and Ketone Formation in the Suckling Rat. M. A. Wells. Fed. Proceedings 44, 2365-2368 (1985).

56.      Modulation of Membrane Fluidity in the Primate (Macaca mulatta) Corpus Luteum: Correlation with Changes in Gonadotropin Binding. D. R. Danforth, M. A. Wells, and R. L. Stouffer, Endocrinology 77, 755-761 (1985).

57.      Dihexanolyphosphatidylethanolamine: Effect of Head Group Charge on Rates of Alkaline and Phospholipase A₂ Catalyzed Hydrolyses. P. Kanda and M. A. Wells, Chem. Phys. Lipids 39, 31-39 (1986).

58.      Changes in Lipoprotein Composition during Larval-Pupal Metamorphosis of an Insect, Manduca sexta. S. V. Prasad, R. O. Ryan, J. H. Law and M. A. Wells, J. Biol. Chem. 261, 558-562 (1986).

59.      Lipoprotein Interconversions in an Insect, Manduca sexta. R. O. Ryan, S. V. Prasad, E. J. Henriksen, M. A. Wells and J. H. Law, J. Biol. Chem. 261, 563-568 (1986).

60.      Lipid Transfer Protein from Manduca sexta. R. O. Ryan, M. A. Wells, and J. H. Law. Biochem. Biophys. Res. Commun. 136, 260-265 (1986).

61.      Halothane-Induced Changes in Acetylcholine Receptor Channel Kinetics are Attenuated by Cholesterol. J. Lechleiter, M. Wells and R. Gruener, Biochim. Biophys. Acta 856, 640-645 (1986).

62.      Studies on Vitellogenin from the Tobacco Hornworm, Manduca sexta. E. O. Osir, M. A. Wells, and J. H. Law. Arch. Insect Biochem. Physiol. 3, 217-233 (1986).

63.      Physical and Surface Properties of Insect Apolipophorin III. J. K. Kawooya, S. C. Meredith, M. A. Wells, F. J. Kezdy, and J. H. Law. J. Biol. Chem. 261, 13588-13591 (1986).

64.      Lipoprotein Biosynthesis in the Larvae of the Tobacco Hornworm, Manduca sexta. S. V. Prasad, G. J. P. Fernando-Warnakulasuriya, M. Sumida, J. H. Law, and M. A. Wells. J. Biol. Chem. 261, 17174-17176 (1986).

65.      The Role of Apolipophorin-III in in vivo Lipoprotein Interconversions in Adult Manduca sexta. M. A. Wells, R. O. Ryan, J. K. Kawooya, and J. H. Law, J. Biol. Chem. 262, 4172-4176 (1987).

66.      Intact Biliary Excretion of Gastrically Administered Prostaglandin F₂ in Rats: Developmental Differences. A. D. Bedrick, M. A. Wells, D. L. Ford and O. Koldovsky, Am. J. Physiol. 253, G787-G792 (1987).

67.      Primary Structure and Comparative Sequence Analysis of an Insect Apolipoprotein: Apolipophorin-III from Manduca sexta. K. D. Cole, G. J. P. Fernando-Warnakulasuriya, M. S. Boguski, M. Freeman, J. I. Gordon, W. A. Clark, J. H. Law and M. A. Wells, J. Biol. Chem. 262, 11794-11800 (1987).

68.      Changes in Lipophorin Composition during the Fourth to Fifth Instar Molt of Manduca sexta. K. Tsuchida, S. V. Prasad, and M. A. Wells, Insect Biochem. 17, 1139-1141 (1987).

69.      Effect of Dietary Lipid Content on Lipid Transport and Storage during Larval Development of Manduca sexta. G. J. P. Fernando-Warnakulasuriya, K. Tsuchida and M. A. Wells, Insect Biochem. 18, 211-214 (1988).

70.      Primary Structure of Apolipophorin-III from the Migratory Locust, Locusta migratoria: Potential Amphipathic Structures and Evolution of an Insect Apolipoprotein. M. R. Kanost, M. S. Boguski, M. Freeman, J. I. Gordon, G. R. Wyatt and M. A. Wells, J. Biol. Chem. 263, 10568-10573 (1988).

71.      Digestion, Absorption, Transport and Storage of Fat during the Last Larval Instar of Manduca sexta. Changes in the Role of Lipophorin in the Delivery of Dietary Lipid to the Fat Body. K. Tsuchida and M. A. Wells, Insect Biochem. 18, 263-268 (1988).

72.      Sequential Structural Changes in the Fat Body of the Tobacco Hornworm, Manduca sexta, during the Fifth Larval Stadium. E. Willott, L. K. Bew, R. B. Nagle and M. A. Wells, Tissue and Cell 20, 635-643 (1988).

73.      Gene Structure, cDNA Sequence, and Developmental Regulation of a Low Molecular Weight Hemolymph Protein from Locusta migratoria. M. R. Kanost, J. Y. Bradfield, K. E. Cook, J. Locke, M. A. Wells and G. R. Wyatt, Arch. Insect Biochem. Physiol. 8, 203-217 (1988).

74.      Isolation and Characterization of Lipophorin from Drosophila melanogaster Larvae. G. J. P. Fernando-Warnakulasuriya and M. A. Wells, Arch. Insect Biochem. Physiol. 8, 243-248 (1988).

75.      Identification and Characterization of a Novel Post Larval Hemolymph Protein from Manduca sexta. R. O. Ryan, K. D. Cole, J. K. Kawooya, M. A. Wells and J. H. Law, Arch. Insect Biochem. Physiol. 9, 81-90 (1988).

76.      Facilitated Diacylglycerol Exchange between Insect Hemolymph Lipophorins. Properties of Manduca sexta Lipid Transfer Particle. R. O. Ryan, K. R. Senthilathipan, M. A. Wells and J. H. Law, J. Biol. Chem. 263, 14140-14145 (1988).

77.      Crystallization and Preliminary Analysis of Crystals of Apolipophorin III Isolated from Locusta migratoria. H. M. Holden, M. R. Kanost, J. H. Law, I. Rayment and M. A. Wells, J. Biol. Chem. 263, 3960-3962 (1988).

78.      Primary Structure of a Member of the Serpin Superfamily of Proteinase Inhibitors from an Insect, Manduca sexta. M. R. Kanost, S. V. Prasad and M. A. Wells, J. Biol. Chem. 264, 965-972 (1989).

79.      A Strategy for Solubilizing Delipidated Apolipoprotein with Lysophosphatidylcholine and Reconstitution with Phosphatidylcholine. J. K. Kawooya, M. A. Wells and J. H. Law, Biochemistry 28, 6658-6667 (1989).

80.      Rates of Triolein Absorption in Suckling and Adult Rats. C. A. Flores, S. A. O. Hing, M. A. Wells and O. Koldovsky, Amer. J. Physiol. 257, G823-829 (1989).

81.      cDNA and Gene Sequence of Manduca sexta Arylphorin, an Aromatic Amino Acid-Rich Larval Serum Protein:  Homology to Arthropod Hemocyanins. E. Willott, X-Y. Wang and M. A. Wells, J. Biol. Chem. 264, 19052-19059 (1989).

82.      Effect of Diet on Triolein Absorption in the Weanling Rat. C. A. Flores, P. M. Brannon, M. A. Wells, M. Morrill and O. Koldovsky, Amer. J. Physiol. 258, G38-G44 (1990).

83.      Isolation and Characterization of a Lipoprotein Receptor from the Fat Body of an Insect, Manduca sexta. K. Tsuchida and M. A. Wells, J. Biol. Chem. 265, 5761-5767 (1990).

84.      A Comparison of Adult and Larval Manduca sexta Apolipophorin-III. K. D. Cole and M. A. Wells, Insect Biochem. 20, 373-380 (1990).

85.      The Structure of the Apolipophorin-III Gene from Manduca sexta. K. D. Cole, A. F. Smith and M. A. Wells, Insect Biochem. 20, 381-388 (1990).

86.      Adipokinetic Hormone Causes Formation of a Low Density Lipophorin in the House Cricket, Acheta domesticus. L. M. Strobel, M. R. Kanost, R. Ziegler and M. A. Wells, Insect Biochem. 20, 859-863 (1990).

87.      Molecular Structure of an Apolipoprotein Determined at 2.5 Å Resolution. D. R. Breiter, M. R. Kanost, M. M. Benning, J. H. Law, M. A. Wells, I. Rayment and H. M. Holden, Biochemistry 30, 603-608 (1991).

88.      Peptide Amphipathy: A New Approach to Potential Insecticides. D. R. Frohlich and M. A. Wells, Int. J. Peptide Protein Res. 37, 2-6 (1991).

89.      cDNA and Deduced Amino Acid Sequence of the Blood Meal-Induced Trypsin from the Mosquito, Aedes aegypti. C. Barillas-Mury, R. Graf, H. H. Hagedorn, and M. A. Wells, Insect Biochem. 21, 825-831 (1991).

90.      Isolation, Characterization, and cDNA Sequence of Two Fatty Acid-Binding Proteins from the Midgut of Manduca sexta Larvae. A. F. Smith, K. Tsuchida, E. Hanneman, T. C., Suzuki, and M. A. Wells, J. Biol. Chem. 267, 380-384 (1992).

91.      Isolation and Characterization of Two Follicle-Specific Proteins from Eggs of Manduca sexta. K. Tsuchida, J. K. Kawooya, J. H. Law and M. A. Wells, Insect Biochem. Molec. Biol. 22, 89-98 (1992).

92.      Oxygen-Carrying Perfluorochemical Emulsions Improve Insect Fat Body Culture Performance. F. G. Noriega and M. A. Wells, Insect Biochem. Molec. Biol. 22, 585-590 (1992).

93.      Diet, Age and Intestinal Bile Acids in Pigs. C. A. Flores, M. A. Wells, M. Morrill, S. A. Bustamante and O. Koldovsky, Nutrition 8, 418-420 (1992).

94.      Crystallization, Structure Determination and Least Squares Refinement to 1.75 Å Resolution of the Fatty Acid-Binding Protein Isolated from Manduca sexta. L. M. M. Benning, A. F. Smith, M. A. Wells and H. M. Holden, J. Molec. Biol. 228, 208-219 (1992).

95.      Gene Synthesis, Bacterial Expression and ¹H NMR Spectroscopic Studies of the Rat Outer Mitochondrial Membrane Cytochrome b₅. M. Rivera, C. Barillas-Mury, K. A. Christensen, J. W. Little, M. A. Wells and F. A. Walker, Biochemistry 31, 12233-12240 (1992).

96.      Mediterranean Fruit Fly, Ceratitis capitata (Wiedemann), Mitochondrial DNA: Genes and Secondary Structures for Six t-RNAs. D. R. Frohlich, A. S. Robinson and M. A. Wells, Insect Molec. Biol. 1, 165-169 (1993).

97.      p-Nitrophenylacetate Hydrolysis by Honey Bee Esterase: Kinetics and Inhibition. J. F. Spoonamore, D. R. Frohlich and M. A. Wells, Xenobiotica 23, 279-284 (1993).

98.      Cloning and Sequencing of the Blood Meal-Induced Late Trypsin Gene from the Mosquito Aedes aegypti and Characterization of the Upstream Regulatory Region. C. Barillas-Mury and M. A. Wells, Insect Molec. Biol. 2, 7-12 (1993).

99.      Polymorphic cDNAs Encode for the Methionine-Rich Storage Protein from Manduca sexta. X-Y. Wang, D. R. Frohlich and M. A. Wells, Insect Molec. Biol. 2, 13-20 (1993).

100.   A Comparison of Three Methods for Isolating RNA from Mosquitoes. F. G. Noriega and M. A. Wells. Insect Molec. Biol. 2, 21-24 (1993).

101.   Purification of a Carotenoid-Binding Protein from the Midgut of the Silkworm, Bombyx mori. Z. E. Jouni and M. A. Wells. Ann. N.Y. Acad. Sci. 691, 210-212 (1993).

102.   Metabolic Fate and Turnover Rate of Hemolymph Free Fatty Acids in Adult Manduca sexta. J. L. Soulages and M. A. Wells, Insect Biochem. Molec. Biol. 24, 79-86 (1994).

103.   Cation-Promoted Cyclic Voltammetry of Recombinant Rat Outer Mitochondrial Membrane Cytochrome b₅ at a Gold Electrode Modified with 8-Mercaptopropionic Acid. M. Rivera, M. A. Wells and F. A. Walker, Biochemistry 33, 2161-2170 (1994).

104.   Effect of Diacylglycerol Content on some Physiochemical Properties of the Insect Lipoprotein, Lipophorin. Correlation with the Binding of Apolipophorin-III. J. L. Soulages and M. A. Wells, Biochemistry 33, 2356-2362 (1994).

105.   Codon Usage among Lepidopteran Hemolymph Proteins. D. R. Frohlich and M. A. Wells, J. Molec. Evol., 38, 476-481 (1994).

106.   Sequence of Three cDNAs Encoding an Alkaline Midgut Trypsin from Manduca sexta. A. M. Peterson, C. V. Barillas-Mury and M. A. Wells. Insect Biochem. Molec. Biology, 24, 463-471 (1994).

107.   Hydration and Localization of Diacylglycerol in the Insect Lipoprotein, Lipophorin. J. L. Soulages, M. Rivera, F. A. Walker and M. A. Wells, Biochemistry 33, 3245-3251 (1994).

108.   Dietary Control of Late-Trypsin Gene Transcription in Aedes aegypti. F. G. Noriega, C. V. Barillas-Mury and M. A. Wells, Insect Biochem. Molec. Biol. 24, 627-631 (1994).

109.   Purification and Properties of a Phosphorylatable Triacylglycerol Lipase from the Fat Body of an Insect, Manduca sexta. E. L. Arrese and M. A. Wells, J. Lipid Res. 35, 1652-1660 (1994)

110.   Exchangeable Apolipoproteins of Insects Share a Common Structural Motif. A. F. Smith, L. M. Owens, L. M. Strobel, H. Chen, M. R. Kanost, E. Hanneman and M. A. Wells, J. Lipid Res. 35, 1976-1984 (1994).

111.   Purification and Properties of Glycogen-Phosphorylase from the Fat Body of Larval Manduca sexta. E. L. Arrese, B. I. Rojas-Rivas and M. A. Wells, Insect Biochem. Molec. Biol. 25, 209-216 (1995).

112.   Early Trypsin Activity is Part of the Signal Transduction System that Activates Transcription of the Late Trypsin Gene in the Midgut of the Mosquito, Aedes aegypti. C. V. Barillas-Mury, F. G. Noriega and M. A. Wells, Insect Biochem. Molec. Biol. 25, 241-246 (1995).

113.   Isolation and Characterization of Apolipophorin-III from the Giant Water Bug (Lethocerus medius). M. R. Kanost, K. A. Sparks and M. A. Wells, Insect Biochem. Molec. Biol. 25, 759-764 (1995).

114.   Purification, Characterization and cDNA Sequence of an Alkaline Chymotrypsin from the Midgut of Manduca sexta. A. M. Peterson, G. J. P. Fernando and M. A. Wells, Insect Biochem. Molec. Biol. 25, 765-774 (1995).

115.   Low Concentrations of Diacylglycerol Promote the Binding of Apolipophorin-III to a Phospholipid Surface: A Surface Plasmon Resonance Spectroscopy Study. J. L. Soulages, Z. Salamon, M. A. Wells and G. Tollin, Proc. Natl. Acad. Sci. U.S.A. 92, 5650-5654 (1995).

116.   Aedes aegypti Midgut Early Trypsin Is Post-transcriptionally Regulated by Blood Feeding. F. G. Noriega, J. E. Pennington, C. Barillas-Mury, X.-Y. Wang and M. A. Wells,  Insect  Molec. Biol.5, 25-29 (1996).

117.   Synthesis of sn-1, 2-Diacylglycerols by Monoacylglycerol Acyltransferase from Manduca sexta Fat Body. E. L. Arrese. B. Rojas-Rivas, and M. A. Wells, Arch. Insect Biochem. Physiol. 31, 325-335 (1996).

118.   Early Trypsin, a Female-specific Midgut Protease in Aedes Aegypti: Isolation, Amino-terminal Sequence Determination, and Cloning and Sequencing of the Gene. F. G. Noriega, X.-Y. Wang, J. E. Pennington, C. V. Barillas-Mury and M. A. Wells, Insect Biochem. Molec. Biol. 26, 119-126 (1996).

119.   Role of Diacylglycerol and Apolipophorin-III in Regulating the Physiochemical Properties of the Lipophorin Surface: Metabolic Implications. J. L. Soulages, R. van Antwerpen, and M. A. Wells, Biochemistry 35, 5191-5198 (1996).

120.   Mitochondrial Cytochrome C Oxidase Subunit I of Manduca sexta and a Comparison with Other Invertebrate Genes. D. R. Frohlich, B. A. Steveneson, A. M. Peterson and M. A. Wells, Comp. Biochem. Physiol 113B, 785-788 (1996).

121.   Purification and Partial Characterization of a Lutein-Binding Protein from the Midgut of the Silkworm, Bombyx mori. Z. E. Jouni and M. A. Wells, J. Biol. Chem. 271, 14722-14726 (1996).

122.   The Use of Decapitated Insects to Study Lipid Mobilization in Adult Manduca sexta: Effects of Adipokinetic Hormone and Trehalose on Fat Body Lipase Activity. E. L. Arrese, B. I. Rojas-Rivas and M. A. Wells, Insect Biochem. Molec. Biol. 26, 775-782 (1996).

123.   The Precursor Protein of the Structural Apolipoproteins of Lipophorin: cDNA and Deduced Amino Acid Sequence. K. Sundermeyer, J. K. Hendricks, S. V. Prasad, and M. A. Wells, Insect Biochem. Molec. Biol. 26, 735-738 (1996).

124.   Juvenile Hormone Controls Early Trypsin Gene Transcription in the Midgut of Aedes aegypti. F. G. Noriega, D. K. Shah and M. A. Wells, Insect Molec. Biol. 6, 63-66 (1997).

125.   Adipokinetic Hormone-Induced Lipolysis in the Fat Body of an Insect, Manduca sexta: Synthesis of sn-1,2-diacylglycerols. E. L. Arrese and M. A. Wells J. Lipid Res. 38, 68-76 (1997).

126.   Purification and Properties of a Lipid Transfer Particle from Bombyx mori. Comparison to the Lipid Transfer Particle from Manduca sexta. K. Tsuchida, J. L. Soulages, A. Moribayashi, K. Suzuki, H. Maekawa and M. A. Wells, Biochim. Biophys. Acta 1337, 57-65 (1997).

127.   Biological Effects of Canatoxin, a Plant Toxic Protein, in Different Insect Models. Evidence for a Proteolytic Activation of the Toxin by Insect Cathepsin-Like Enzymes. C. R. Carlini, A. E. A. Oliveira, P. Azambuja, J. Xavier-Filho, and M. A. Wells, J. Econ. Entomol. 90, 340-348 (1997).

128.   cDNA Cloning and Pattern of Expression of an Adult, Female-Specific Chymotrypsin from Aedes aegypti Midgut. Q. Jiang, M. Hall and M. A. Wells Insect Biochem. Molec. Biol. 27, 283-289 (1997).

129.   Role of Glycosylation in the Lipid-Binding Activity of the Exchangeable-Apolipoprotein, Apolipophorin-III. J. L. Soulages, J. Pennington, O. Bendavid, and M. A. Wells, Biochem. Biophys. Res. Commun. 243, 372-376 (1998).

130.   Calcium and cAMP are Second Messengers in the Adipokinetic Hormone-Induced Lipolysis of Triacylglycerols in the Manduca sexta Fat Body. E. L. Arrese, M. T. Flowers, J. L. Gazard and M. A. Wells, J. Lipid Res. 40, 556-564 (1999).

131.   Increase in the Size of the Amino Acid Pool is Sufficient to Activate Translation of Early Trypsin mRNA in Aedes aegypti Midgut. F. G. Noriega, A. E. Colonna and M. A. Wells Insect Biochem. Molec. Biol. 29, 243-247 (1999).

132.   cDNA and Deduced Amino Acid Sequence of Apolipophorin-IIIs from Bombyx mori and Bombyx mandarina. Y. Yamauchi, C. Hoeffer, A. Yamamoto, H. Takeda, R. Ishihara, H. Maekawa, R. Sato, S. Su-Il, M. Sumida, M. A. Wells and K. Tsuchida, Arch. Insect Biochem. Physiol. 43, 16-21 (2000).

133.   Recombinant Juvenile Hormone Esterase, an Effective Tool to Modify Juvenile Hormone-Dependent Gene Expression in Mosquitoes. K. A. Edgar, F. G. Noriega, B. C. Bonning and M. A. Wells, Insect Molec. Biol. 9, 27-31 (2000).

134.   cDNA and Deduced Amino Acid Sequence of Apolipophorin-III from Agrius convolvuli, Y. Yamauchi, J. Ragland, H. Maekawa, R. Sato, K. Hamano, M. A. Wells, and K. Tsuchida, Appl. Entomol. Zool. 35, 21-26 (2000).

135.   Characterization of Lipophorin Binding to the Midgut of Larval Manduca sexta. K. C. Gondim and M. A. Wells, Insect Biochem. Molec. Biol. 30, 405-423 (2000).

136.   Developmental Changes in the Response of Larval Manduca sexta Fat Body Glycogen Phosphorylase to Starvation, Stress and Octopamine. J. R. Meyer-Fernandes, K. C. Gondim and M. A. Wells, Insect Biochem. Molec. Biol. 30, 415-422 (2000).

137.   Allosteric Effectors and Trehalose Protect Larval Manduca sexta Fat Body Glycogen Phosphorylase B against Thermal Denaturation. J. R. Meyer-Fernandes, E. L. Arrese, and M. A. Wells, Insect Biochem. Molec. Biol. 30, 473-478 (2000).

138.   a-Cyclodextrin Extracts Diacylglycerol from Insect High-Density Lipoproteins. Z. E. Jouni, J. Zamora, M. Snyder, W. R. Montfort, A. Weichsel and M. A. Wells, J. Lipid. Res. 41, 933-939 (2000).

139.   Metabolic Pathways for Diacylglycerol Biosynthesis and Release in the Midgut of Larval Manduca sexta. L. E. Canavoso and M. A. Wells, Insect Biochem. Molec. Biol. 30, 1173-1180 (2000).

140.   Ectonucleotide Diphospohydrolase Activities in Hemocytes of Larval Manduca sexta. J. R. Meyer-Fernandes, H. Lanz-Mendoza, K. C. Gondim, E. Willott, and M. A. Wells. Arch. Biochem. 382 152-159 (2000).

141.   Diacylglycerol Transport in the Insect Fat Body: Evidence of Involvement of Lipid Droplets and the Cytosolic Fraction. E. L. Arrese, J. L. Gazard, M. T. Flowers and M. A. Wells, J. Lipid Res.42 224-234 (2001).

142.   Fat Body Fructose-2, 6-Bisphosphate Content and Phosphorylase Activity Correlate with Changes in Hemolymph Glucose Concentration during Fasting and Re-feeding in Larval Manduca sexta. J. R. Meyer-Fernandes, C. P. Clark, K. C. Gondim and M. A. Wells, Insect Biochem. Molec. Biol. 31 165-170 (2001).

143.   Neuroendocrine Factors Affecting the Steady State Levels of Early Trypsin mRNA in Aedes aegypti. F. G. Noriega, K. A. Edgar, W. G. Goodman, D. K. Shah, and M. A. Wells, J. Insect Physiol. 47 515-522 (2001).

144.   Role of Lipid Transfer Particle in Delivery of Diacylglycerol from Midgut to Lipophorin in Larval Manduca sexta. L. E. Canavoso and M. A. Wells, Insect Biochem. Molec. Biol. 31, 783-90 (2001).

145.    Midgut Exopeptidase Activities in Aedes aegypti are induced by Blood Feeding. F. G. Noriega, K. A. Edgar, R. Bechet, and M. A. Wells. J. Insect Physiol. 48, 205-212 (2002).

146.   Absorption and Tissue Distribution of Cholesterol in Manduca sexta. Z. E. Jouni, J. Zamora and M. A. Wells, Arch. Insect Biochem. Physiol. 49, 167-175 (2002).

147.   b-Cyclodextrin Facilitates Cholesterol Efflux from Larval Manduca sexta Fat Body and Midgut in vitro. Z. E. Jouni, B. McGill and M. A. Wells. Comp. Biochem. Physiol.  B 132, 699–709 (2002).

148.   Cholesterol Efflux from Larval Manduca sexta Fat Body: High Density Lipophorin as the Acceptor. Z. E. Jouni, H. K. Yun and M. A. Wells, J. Insect Physiol 48 609–618 (2002).

149.   Triacylglycerol-Rich Lipophorins are found only in the Dipteran Infraorder Culicomorrpha. J. E. Pennington and M. A. Wells. J. Insect Sci.  2.15. Available online: insectscience.org/2.15.

150.    Characterization of Cholesterol Transport from Midgut to Fat Body in Manduca sexta Larvae H. K. Yun, Z. E. Jouni and M. A. Wells, Insect Biochem. Molec. Biol.  32, 1151-1158 (2002).

151.   Comparative Genome and Proteome Analysis of Anopheles gambiae and Drosophila melanogaster. E. M. Zdobnov, C. von Mering, I. Letunic, D. Torrents, M. Suyama, R.R. Copley, G. K. Christophides, D. Thomasova, R.A. Holt, G.M. Subramanian, H.-M Mueller, G. Dimopoulos, J.H. Law, M.A. Wells, E. Birney, R. Charlab, A.L. Halpern, E. Kokoza, C.L. Kraft, Z. Lai, S. Lewis, C. Louis, C. Barillas-Mury, D. Nusskern, G.M. Rubin, S.L. Salzberg, G.G. Sutton, P. Topalis, R. Wides, P. Wincker, M. Yandell, F.H. Collins, J. Ribeiro, W.M. Gelbart, F.C. Kafatos, and P. Bork, Science 298, 149-159 (2002).

152.   The Role of Hemolymph Proline as a Transient Nitrogen Sink during Blood Meal Digestion by the Mosquito, Aedes aegypti. D.A. Goldstrom J.E. Pennington and M.A. Wells, J. Insect Physiol.  49, 115-121 (2003).

153.   Transfer of Cholesterol and Diacylglycerol from Lipophorin to Bombyx mori Ovarioles in vitro: Role of the Lipid Transfer Particle. Z.E. Jouni, N. Takada, J. Gazard, H. Maekawa, M.A. Wells, and K. Tsuchida. Insect Biochem. Molec. Biol.  33, 145-153 (2003).

154.   The Phylogenetic Distribution of Sphingomyelinase D Activity in Venoms of Haplogyne Spiders. G.J. Binford and M.A Wells. Comp Biochem Physiol B Biochem Mol Biol. 135, 25-33 (2003).

155.   Proline can be utilized as an Energy Substrate during Flight of Aedes aegypti Females. P.Y. Scaraffia and M.A. Wells, J. Insect Physiol. 49, 591-601(2003).

156.   Metabolic Fate of [¹⁴C]-Labeled Meal Protein Amino Acids in Aedes aegypti Mosquitoes, G. Zhou, M. Flowers, K. Friedrich, J. Horton, J. E. Pennington and M. A. Wells, J. Insect Physiol 50, 337-349 (2004).

157.   Lipid Transfer Particle Mediates the Delivery of Diacylglycerol from Lipophorin to Fat Body in Larval Manduca sexta. L. E. Canavoso, H. K. Yun, Z. E. Jouni and M. A. Wells J. Lipid Res. 45, 456-465 (2004).

158.